Treatment of nasolabial folds


The folds of bitterness are wrinkles that start from the corner of the mouth and descend towards the chin, the worsening of which is gradual and inevitable.
These are the wrinkles that age the face and give an air of bad mood.

The appearance of the fold of bitterness is multifactorial:
- The contraction of the facial skin muscles, especially the DAO muscle which pulls the corners of the lips downwards.
- Skin sagging and infero-internal ptosis of internal fat.
- The loss of support by the fat that melts at the level of the labial mouth, and bone aging.

Several stages exist

Stage 0 

No groove


Stage 4 

Very severe nasolabial folds


Stage 1 

Light nasolabial folds


Stage 2 

Moderate nasolabial folds


Stage 3 

Severe nasolabial folds


Hyaluronan anti aging treatment

Hyaluronic acid

Hyaluronic acid is used to lift fallen malarial tissues over time because they are responsible for the appearance of these folds.
So we do not inject the folds directly to avoid weighing down the face.
If after the lift step the fold persists, it is injected.
Depending on the type of fold,  is chosen a hyaluronic acid moderately crosslinked type Restylane or highly crosslinked type RestylanePerlane. The injection is made at the level of the fold and in an imaginary triangle located under the labial commissure, to give a support to the commissures of the lips and to raise them slightly.
The product stays in place between eight months and two years, depending on the severity of the crease, the age of the patient and the product used.


Threads improve or treat the bitterness fold by lifting the ptosed tissues.
They are often associated with injections of hyaluronic acid because they are not enough to lift the fat (they can lift well than the skin) and due to ptosis it is only one of the etiologies of these folds.



My nasogenian fold was very marked. I stumbled upon Doctor Romano’s website, after the consultation, she did a filling at the level of the folds, at the end of the consultation she gave me a textbook with traceability of the product. I felt trustful and the results were up to my expectations.


I am a 30 year-old woman, I wanted to dim the wrinkles of my nasogenian folds, Doctor Romano did an injection, the result was instantaneous. I feel rejuvenated.


My naogenian folds were very obvious, I went to see Doctor Romano to get rid of my obsession, she perfectly masters the technique. Thank you very much.


I tried many creams to dim the wrinkles on the side of the nose, with no success. A single injection was enough to erase them. Doctor Romano is amazing.


Written by Valeria Romano

Former intern at the Hospitals of Paris Graduate of the Faculty of Medicine, University of Paris 7 – Paris Diderot Registered with the medical board of Paris, n° 75/80452 More informations

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